HLA Gene Characterisation
Full length HLA gene characterisation via dual redundant reference sequencing
- for registration of new alleles and research projects -
Novel HLA alleles are frequently discovered, but the characterisation of the complete allelic sequence and subsequent submission to the IMGT/HLA database remains a tedious and cumbersome process. By combining the strengths of two complementary sequencing technologies SMRT sequencing on Pacific Biosciences instruments and shotgun sequencing on Illumina instruments, we achieve fully phased zero-error sequence characterisation from 5’ to 3’UTR.
Using largely automated methods for submitting new alleles to the IMGT/HLA database, we provide characterisation and submission of dual redundantly sequenced alleles as a service.
